Click Here to Download: https://ouo.io/CT0gEu Principles of Clinical Cancer Genetics A Handbook from the Massachusetts General Hospital Publisher: Springer Print ISBN: 9780387938448, 0387938443 eText ISBN: 9780387938462, 038793846X Copyright year: 2010 Format: EPUB Available from $ 189.00 USD SKU 9780387938462 Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.
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