Click Here to Download: https://ouo.io/Ljwif7 Bioreduction in the Activation of Drugs Proceedings of the Second Biochemical Pharmacology Symposium, Oxford, UK, 25-26 July 1985 By: P. Alexander Publisher: Pergamon Print ISBN: 9780080320304, 0080320309 eText ISBN: 9781483190839, 1483190838 Copyright year: 1986 Format: PDF Available from $ 31.95 USD SKU 9781483190839 Bioreduction in the Activation of Drugs covers the proceedings of the Second Biochemical Pharmacology Symposium. The book presents papers that cover the applications of bioreduction in drug activation, along with its concerns. The text first presents materials about enzymology, such as overview of enzyme systems involved in bioreduction of drugs and in redox cycling, and reductive role of glutathione in the redox cycling of oxidizable drugs. Next, the book covers papers on bacterial and parasites infection, which include reduction by the gut microflora of animals and human and reduction of nitroimidazoles in vitro and DNA damage. The remaining articles deal with cancer treatment, such as hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer, and the biological properties of reduced nitroheterocyclics and possible underlying biochemical mechanisms. The text will be of great use to researchers and practitioners of medicine, pharmacology, and biochemistry.
