Click Here to Download: https://ouo.io/1NoyEw Deep Brain Stimulation Indications and Applications By: Kendall H. Lee Publisher: Jenny Stanford Publishing Print ISBN: 9789814669894, 981466989X eText ISBN: 9781315341095, 1315341093 Edition: 1st Copyright year: 2016 Format: EPUB Available from $ 23.18 USD SKU 9781315341095R90 Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.
