Click Here to Download: https://ouo.io/XZ25JE Developmental Origins of Health and Disease (DOHaD) From Biological Basis to Clinical Significance By: Takeo Kubota Publisher: Springer Print ISBN: 9789811055256, 9811055254 eText ISBN: 9789811055263, 9811055262 Copyright year: 2018 Format: EPUB Available from $ 149.00 USD SKU 9789811055263 This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.
