Click Here to Download: https://ouo.io/Cr9J5t Formulating Poorly Water Soluble Drugs By: Robert O. Williams III Publisher: Springer Print ISBN: 9783319426075, 3319426079 eText ISBN: 9783319426099, 3319426095 Edition: 2nd Copyright year: 2016 Format: PDF Available from $ 269.00 USD SKU 9783319426099 The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop
