Click Here to Download: https://ouo.io/yPHiX7 IgE Antibodies: Generation and Function By: Juan J. Lafaille Publisher: Springer Print ISBN: 9783319137247, 3319137247 eText ISBN: 9783319137254, 3319137255 Copyright year: 2015 Format: EPUB Available from $ 149.00 USD SKU 9783319137254 This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
