Click Here to Download: https://ouo.io/G6RB4oW Linkage Thermodynamics of Macromolecular Interactions By: Richards, Frederic M. Publisher: Academic Press Print ISBN: 9780120342518, 0120342510 eText ISBN: 9780120342518, 9780080582245, 0080582249 Pages: 473 Format: PDF Available from $ 175.00 USD SKU 9780120342518 This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he laid down the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.