Mechanisms of Chemical Carcinogenesis By: D. E. Hathway Publisher: Elsevier Butterworth Heinemann Print ISBN: 9780408115704, 040811570X eText ISBN: 9781483192468, 1483192466 Copyright year: 1986 Format: PDF Available from $ 31.95 USD SKU: 9781483192468 Mechanisms of Chemical Carcinogenesis provides information pertinent to the fundamental mechanisms of chemical carcinogenesis. This book surveys the interactions of chemical carcinogens with native DNA, the activation of normal cellular sequences, and the transforming role of the activated genes. Organized into seven chapters, this book begins with an overview of the relationship between the incidence of lung cancer and the frequency and duration of cigarette smoking. This text then examines the concept that carcinogens may require metabolic activation before they initiate carcinogenesis. Other chapters consider the structure of the nucleoside adducts resulting from the hydrolysis of salmon-sperm DNA and rat-liver ribosomal RNA. This book discusses as well the persistence of nucleoside analogues in target-tissue nucleic acid. The final chapter deals with mutational theory. This book is a valuable resource for workers involved with cancer research, toxicology, and molecular biology. Specialists in drug development, industrial hygiene and occupational medicine will also find this book useful. SKU: 9780408115704 Download now: https://ebookscoffee.sellpass.io/products/Mechanisms-of-Chemical-Carcinogenesis
