Click Here to Download: https://ouo.io/Mr1OdHL Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells By: T.E. Gram Publisher: Pergamon Print ISBN: 9780080411774, 0080411770 eText ISBN: 9781483287621, 1483287629 Copyright year: 1993 Format: PDF Available from $ 72.95 USD SKU 9781483287621 Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.