Metabolic Activation And Toxicity Of Chemical Agents To Lung Tissue And Cells

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    Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells
    By: T.E. Gram
    Publisher:
    Pergamon
    Print ISBN: 9780080411774, 0080411770
    eText ISBN: 9781483287621, 1483287629
    Copyright year: 1993
    Format: PDF
    Available from $ 72.95 USD
    SKU 9781483287621
    Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.
     

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