Link Download ebook Free: https://ouo.io/h5yYBd Protein Folding in Silico: Protein Folding Versus Protein Structure Prediction By: Roterman-Konieczna, I Publisher: Woodhead Publishing Print ISBN: 9781907568176, 1907568174 eText ISBN: 9781907568176, 9781908818256, 1908818255 Pages: 240 Format: PDF Available from $ 205.00 USD SKU 9781907568176 Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the fuzzy oil drop model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks. Discusses a range of ab initio models for protein structure prediction Introduces a unique model based on experimental observations Describes various methods for the quantitative assessment of the presented models from the viewpoint of information theory
