Rapid Cell Magnetisation Using Cationised Magnetoferritin

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    Rapid Cell Magnetisation Using Cationised Magnetoferritin
    By: Sara Correia Carreira
    Publisher:
    Springer
    Print ISBN: 9783319603322, 3319603329
    eText ISBN: 9783319603339, 3319603337
    Copyright year: 2017
    Format: PDF
    Available from $ 109.00 USD
    SKU 9783319603339
    Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.
     

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