Rational Basis for Clinical Translation in Stroke Therapy By: Giuseppe Micieli Publisher: routledge Print ISBN: 9781138374867, 1138374865 eText ISBN: 9781466594982, 1466594985 Edition: 1st Copyright year: 2015 Format: PDF Available from $ 23.18 USD SKU 9781466594982R90 Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy. Researchers in the field now face the crucial need to develop effective stroke therapies and successfully translate novel strategies into the clinical setting. Ratio Download ebook: https://ouo.io/apGwrLA