Click Here to Download: https://ouo.io/WM31Oa Stereoselective Syntheses of Tetrahydropyrans Applications to the Synthesis of ( )-Leucascandrolide A, ( )-Dactylolide and (±)-Diospongin A By: Kiyoun Lee Publisher: Springer Print ISBN: 9783319044613, 3319044613 eText ISBN: 9783319044620, 3319044621 Copyright year: 2014 Format: EPUB Available from $ 99.00 USD SKU 9783319044620 In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including ( )-leucascandrolide A, ( )-dactylolide, and (±)diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology.
