Click Here to Download: https://ouo.io/nkhZEgn The Retina and Circadian Rhythms By: Gianluca Tosini Publisher: Springer Print ISBN: 9781461496120, 1461496128 eText ISBN: 9781461496137, 1461496136 Copyright year: 2014 Format: EPUB Available from $ 149.00 USD SKU 9781461496137 Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.
