Click Here to Download: https://ouo.io/mQ3gzm3 Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility Experiments and Monte Carlo Simulations By: Matthias Würl Publisher: Springer Spektrum Print ISBN: 9783658131678, 3658131675 eText ISBN: 9783658131685, 3658131683 Copyright year: 2016 Format: PDF Available from $ 69.99 USD SKU 9783658131685 Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields.
